mouse LAG3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Lag3.
shADV-263224
Ad-m-LAG3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Lag3 (lymphocyte-activation gene 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD antigen CD223;CD223;LAG-3;Ly66;lymphocyte activation gene 3 protein
Description (eCommerce)
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4 [taken from NCBI Entrez Gene (Gene ID: 3902)]
Description (Vector)
Involved in lymphocyte activation. Binds to HLA class-II antigens.
Gene ID
16768
Gene Name (eCommerce)
lymphocyte-activation gene 3
Gene Name (Vector)
lymphocyte-activation gene 3
Gene Symbol
Lag3
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
Protein Name (eCommerce)
Lymphocyte activation gene 3 protein
RefSeq ID
NM_008479
RefSeq Synonyms
NM_008479, BC120591,
Research Areas
Immune cells & tumor markers,Immune-checkpoints,Immunology,Immuno-Oncology,Signal Transduction,T cell markers
Research Areas (Faceted)
immuno_oncology,immunology,signal_transduction
Species
mouse
Target Sentence
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4 [taken from NCBI Entrez Gene (Gene ID: 3902)]
UniGene ID
Mm.4528
UniProt ID (eCommerce)
Q61790
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.