mouse KCNJ11 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Kcnj11.
shADV-262651
Ad-m-KCNJ11-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kcnj11 (potassium inwardly rectifying channel, subfamily J, member 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Kir6.2; mBIR
Description (Vector)
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Gene ID
16514
Gene Name (Vector)
potassium inwardly rectifying channel, subfamily J, member 11
Gene Symbol
Kcnj11
ORF Size (aa)
1173
RefSeq ID
NM_010602
RefSeq Synonyms
NM_010602, NM_001204411, BC057006, BC052731,
Species
mouse
UniGene ID
Mm.333863
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.