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mouse ITPA shRNA silencing Adenovirus

Name 
Ad-m-ITPA-shRNA
Cat No 
shADV-262481
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Itpa.

shADV-262481
Ad-m-ITPA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Itpa (inosine triphosphatase (nucleoside triphosphate pyrophosphatase)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2010016I08Rik; AU020102; Itp
Description (Vector)
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Gene ID
16434
Gene Name (Vector)
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Gene Symbol
Itpa
ORF Size (aa)
597
RefSeq ID
NM_025922
RefSeq Synonyms
NM_025922, BC094466, BC026508,
Species
mouse
UniGene ID
Mm.21399

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.