Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human ITPA shRNA silencing Adenovirus

Name 
Ad-h-ITPA-shRNA
Cat No 
shADV-212542
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ITPA.

shADV-212542
Ad-h-ITPA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ITPA (inosine triphosphatase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C20orf37; dJ794I6.3; HLC14-06-P; ITPase; My049; NTPase
Description (Vector)
ITPA encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.
Gene ID
3704
Gene Name (Vector)
inosine triphosphatase
Gene Symbol
ITPA
HGNC ID
HGNC:6176
ORF Size (aa)
585
RefSeq ID
NM_033453
RefSeq Synonyms
NM_181493, NM_033453, NM_001324240, NM_001324238, NM_001324237, NM_001324236, NM_001267623, BC010138,
Species
human
UniGene ID
Hs.415299

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.