mouse IRF9 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Irf9.
shADV-262375
Ad-m-IRF9-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Irf9 (interferon regulatory factor 9). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Irf-9; Isgf3g; p48
Description (Vector)
Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Gene ID
16391
Gene Name (Vector)
interferon regulatory factor 9
Gene Symbol
Irf9
ORF Size (aa)
1200
RefSeq ID
NM_008394
RefSeq Synonyms
NM_008394, NM_001159418, NM_001159417, BC012968, BC005435,
Species
mouse
UniGene ID
Mm.2032
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.