mouse IRF8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Irf8.
shADV-262374
Ad-m-IRF8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Irf8 (interferon regulatory factor 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI893568; ICSBP; Icsbp1; interferon consensus sequence binding protein 1; interferon consensus sequence-binding protein; interferon regulatory factor 8; IRF-8; Myls
Description (eCommerce)
Interferon regulatory factor (IRF8) is a member of the IRF family of transcription factors that plays a critical role in immune cell function and development. IRF8 has been shown to be an important regulator of CD8 T-cell differentiation.
Description (Vector)
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system.
Gene ID
15900
Gene Name (eCommerce)
interferon regulatory factor 8
Gene Name (Vector)
interferon regulatory factor 8
Gene Symbol
Irf8
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1275
ORF Size (bp)
1275 bp
Protein Name (eCommerce)
Interferon regulatory factor 8
RefSeq ID
NM_008320
RefSeq Synonyms
NM_008320, NM_001301811, BC005450,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
mouse
Target Sentence
Interferon regulatory factor (IRF8) is a member of the IRF family of transcription factors that plays a critical role in immune cell function and development. IRF8 has been shown to be an important regulator of CD8 T-cell differentiation.
UniGene ID
Mm.334861
UniProt ID (eCommerce)
P23611
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.