mouse HSP90AB1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Hsp90ab1

Gene Name

heat shock protein 90 alpha (cytosolic), class B member 1

Gene ID

15516

Gene Synonyms

90kDa; AL022974; C81438; Hsp84; Hsp84-1; Hsp90; Hspcb

ORF Size

2175 bp

RefSeq#

NM_008302

Gene Description

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

UniGene ID

Mm.2180