mouse HMGCR shRNA silencing Adenovirus

Name 
Ad-m-HMGCR-shRNA
Cat No 
shADV-261466
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Hmgcr.

shADV-261466
Ad-m-HMGCR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hmgcr (3-hydroxy-3-methylglutaryl-Coenzyme A reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HMG-CoAR; Red
Description (Vector)
Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
Gene ID
15357
Gene Name (Vector)
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Gene Symbol
Hmgcr
ORF Size (aa)
2664
ORF Size (bp)
2664 bp
RefSeq ID
NM_008255
RefSeq Synonyms
NM_008255, BC085083,
Species
mouse
UniGene ID
Mm.475623

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.