mouse HES1 shRNA silencing Adenovirus

Name 
Ad-m-HES1-shRNA
Cat No 
shADV-261240
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Hes1.

shADV-261240
Ad-m-HES1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hes1 (hairy and enhancer of split 1 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bHLHb39; Hry
Description (Vector)
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Gene ID
15205
Gene Name (Vector)
hairy and enhancer of split 1 (Drosophila)
Gene Symbol
Hes1
ORF Size (aa)
849
RefSeq ID
NM_008235
RefSeq Synonyms
NM_008235, BC051428, BC018375,
Species
mouse
UniGene ID
Mm.390859

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.