mouse HDAC4 shRNA silencing Adenovirus

Name 
Ad-m-HDAC4-shRNA
Cat No 
shADV-261177
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Hdac4.

shADV-261177
Ad-m-HDAC4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hdac4 (histone deacetylase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
91
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4932408F19Rik; HD4
Description (Vector)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Gene ID
208727
Gene Name (Vector)
histone deacetylase 4
Gene Symbol
Hdac4
ORF Size (aa)
3231
ORF Size (bp)
3231 bp
RefSeq ID
NM_207225
RefSeq Synonyms
NM_207225, BC066052,
Species
mouse
UniGene ID
Mm.318567

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.