mouse KDM6A shRNA silencing Adenovirus

Name
Ad-m-KDM6A-shRNA

Cat No
shADV-257562

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Kdm6a.

shADV-257562

Ad-m-KDM6A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kdm6a (lysine (K)-specific demethylase 6A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Utx

Description (Vector)

Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.

Gene ID

22289

Gene Name (Vector)

lysine (K)-specific demethylase 6A

Gene Symbol

Kdm6a

ORF Size (aa)

4275

ORF Size (bp)

4275 bp

RefSeq ID

NM_009483

RefSeq Synonyms

NM_009483, NM_001310444, BC053433,

Species

mouse

UniGene ID

Mm.257498

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.