mouse KDM6A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Kdm6a.
shADV-257562
Ad-m-KDM6A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kdm6a (lysine (K)-specific demethylase 6A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Utx
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Gene ID
22289
Gene Name (Vector)
lysine (K)-specific demethylase 6A
Gene Symbol
Kdm6a
ORF Size (aa)
4275
ORF Size (bp)
4275 bp
RefSeq ID
NM_009483
RefSeq Synonyms
NM_009483, NM_001310444, BC053433,
Species
mouse
UniGene ID
Mm.257498
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.