mouse RORA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Rora.
shADV-256623
Ad-m-RORA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Rora (RAR-related orphan receptor alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9530021D13Rik; nmf267; Nr1f1; ROR1; ROR2; ROR3; sg; staggerer; tmgc26
Description (Vector)
Orphan nuclear receptor. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. Possible receptor for cholesterol or one of its derivatives.
Gene ID
19883
Gene Name (Vector)
RAR-related orphan receptor alpha
Gene Symbol
Rora
ORF Size (aa)
1383
ORF Size (bp)
1383 bp
RefSeq ID
NM_013646
RefSeq Synonyms
NM_013646, NM_001289917, NM_001289916, BC003757,
Species
mouse
UniGene ID
Mm.427266
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.