mouse D10ERTD610E shRNA silencing Adenovirus

Name
Ad-m-D10ERTD610E-shRNA

Cat No
shADV-256612

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Arhgef25.

shADV-256612

Ad-m-D10ERTD610E-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Arhgef25 (Rho guanine nucleotide exchange factor (GEF) 25). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

2410008H17Rik; D10Ertd610e; GEFT

Description (Vector)

ARHGEF25 may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis (By similarity).

Gene ID

52666

Gene Name (Vector)

Rho guanine nucleotide exchange factor (GEF) 25

Gene Symbol

Arhgef25

ORF Size (aa)

996

ORF Size (bp)

996 bp

RefSeq ID

NM_028027

RefSeq Synonyms

NM_028027, NM_001166413, BC054833,

Species

mouse

UniGene ID

Mm.272230

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.