mouse CCNH shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ccnh.
shADV-254874
Ad-m-CCNH-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ccnh (cyclin H). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6330408H09Rik; AI661354; AV102684; AW538719
Description (Vector)
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Gene ID
66671
Gene Name (Vector)
cyclin H
Gene Symbol
Ccnh
ORF Size (aa)
972
RefSeq ID
NM_023243
RefSeq Synonyms
NM_023243, NM_001347588, NM_001347587, BC038861,
Species
mouse
UniGene ID
Mm.18474
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.