mouse CBY1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cby1.
shADV-254640
Ad-m-CBY1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cby1 (chibby family member 1, beta catenin antagonist). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110014P06Rik; arb1; CBY; Pgea1; PGEA14
Description (Vector)
Inhibits the Wnt/Wingless pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Gene ID
73739
Gene Name (Vector)
chibby family member 1, beta catenin antagonist
Gene Symbol
Cby1
ORF Size (aa)
384
RefSeq ID
NM_028634
RefSeq Synonyms
NM_028634, BC005733,
Species
mouse
UniGene ID
Mm.294441
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.