mouse CBR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cbr1.
shADV-254616
Ad-m-CBR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cbr1 (carbonyl reductase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW261796; Cbr; CR
Description (Vector)
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Gene ID
12408
Gene Name (Vector)
carbonyl reductase 1
Gene Symbol
Cbr1
ORF Size (aa)
834
RefSeq ID
NM_007620
RefSeq Synonyms
NM_007620, BC158029, BC158026, BC012714,
Species
mouse
UniGene ID
Mm.26940
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.