mouse APH1A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Aph1a.
shADV-254509
Ad-m-APH1A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Aph1a (aph1 homolog A, gamma secretase subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6530402N02Rik; APH-1a
Description (Vector)
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Gene ID
226548
Gene Name (Vector)
aph1 homolog A, gamma secretase subunit
Gene Symbol
Aph1a
ORF Size (aa)
744
ORF Size (bp)
744 bp
RefSeq ID
NM_146104
RefSeq Synonyms
NM_146134, NM_146104, BC057865, BC024111, BC012406,
Species
mouse
UniGene ID
Mm.306954
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.