mouse CALCA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Calca.
shADV-254409
Ad-m-CALCA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Calca (calcitonin/calcitonin-related polypeptide, alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
alpha-type CGRP; CA; Calc; Calc1; calcitonin gene-related peptide 1; calcitonin gene-related peptide I; Cgrp; CGRP1; CGRP-1; CGRP-I; Ct; Ctn
Description (eCommerce)
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99JA0].
Description (Vector)
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP|Function: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones|Function: Katacalcin is a potent plasma calcium-lowering peptide.
Gene ID
12310
Gene Name (eCommerce)
calcitonin/calcitonin-related polypeptide, alpha
Gene Name (Vector)
calcitonin/calcitonin-related polypeptide, alpha
Gene Symbol
Calca
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
411
ORF Size (bp)
411 bp
Protein Name (eCommerce)
Calcitonin gene-related peptide 1;Calcitonin
RefSeq ID
NM_007587
RefSeq Synonyms
NM_007587, NM_001305616, NM_001289444, NM_001033954, BC030071, BC028771,
Research Areas
Aging,Cardiology,Cardiovascular,GPCR Signaling,Immunology,Neurobiology,Neurodevelopment,Signal Transduction
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,immunology,neurobiology,signal_transduction
Species
mouse
Target Sentence
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99JA0].
UniGene ID
Mm.4361
UniProt ID (eCommerce)
Q99JA0
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.