mouse BAD shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Bad.
shADV-253590
Ad-m-BAD-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Bad (BCL2-associated agonist of cell death). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI325008; Bbc2
Description (Vector)
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Gene ID
12015
Gene Name (Vector)
BCL2-associated agonist of cell death
Gene Symbol
Bad
ORF Size (aa)
615
RefSeq ID
NM_007522
RefSeq Synonyms
NM_007522, NM_001285453, BC006762,
Species
mouse
UniGene ID
Mm.4387
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.