mouse ARPP19 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Arpp19.
shADV-253075
Ad-m-ARPP19-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Arpp19 (cAMP-regulated phosphoprotein 19). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
19kDa; 2700024H10Rik; ARPP-19; Arpp12; AW559096
Description (Vector)
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.
Gene ID
59046
Gene Name (Vector)
cAMP-regulated phosphoprotein 19
Gene Symbol
Arpp19
ORF Size (aa)
339
RefSeq ID
NM_021548
RefSeq Synonyms
NM_021548, NM_001142655, BC040206,
Species
mouse
UniGene ID
Mm.247837
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.