mouse ARHGAP10 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Arhgap10.
shADV-252928
Ad-m-ARHGAP10-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Arhgap10 (Rho GTPase activating protein 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A930033B01Rik; PSGAP-m; PSGAP-s
Description (Vector)
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).
Gene ID
78514
Gene Name (Vector)
Rho GTPase activating protein 10
Gene Symbol
Arhgap10
ORF Size (aa)
2358
ORF Size (bp)
2358 bp
RefSeq ID
NM_030113
RefSeq Synonyms
NM_030113, BC172679, BC156535,
Species
mouse
UniGene ID
Mm.165974
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.