mouse ADAMTS4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Adamts4.
shADV-252095
Ad-m-ADAMTS4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Adamts4 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADAM-TS4; ADAMTS-2; ADMP-1
Description (Vector)
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu- -Ala-393' site.
Gene ID
240913
Gene Name (Vector)
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
Gene Symbol
Adamts4
ORF Size (aa)
2502
ORF Size (bp)
2502 bp
RefSeq ID
NM_172845
RefSeq Synonyms
NM_172845, BC027773,
Species
mouse
UniGene ID
Mm.475917
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.