mouse ACMSD shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Acmsd.
shADV-251912
Ad-m-ACMSD-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Acmsd (amino carboxymuconate semialdehyde decarboxylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
Gene ID
266645
Gene Name (Vector)
amino carboxymuconate semialdehyde decarboxylase
Gene Symbol
Acmsd
ORF Size (aa)
1011
ORF Size (bp)
1011 bp
RefSeq ID
NM_001033041
RefSeq Synonyms
NM_001033041, BC139281,
Species
mouse
UniGene ID
Mm.25735
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.