mouse TXNRD1 shRNA silencing Adenovirus

Name 
Ad-m-TXNRD1-shRNA
Cat No 
shADV-251525
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Txnrd1.

shADV-251525
Ad-m-TXNRD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Txnrd1 (thioredoxin reductase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
TR; TR1; TrxR1
Description (Vector)
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Gene ID
50493
Gene Name (Vector)
thioredoxin reductase 1
Gene Symbol
Txnrd1
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
RefSeq ID
NM_015762
RefSeq Synonyms
NM_015762, NM_001042523, NM_001042514, NM_001042513, BC037643,
Species
mouse
UniGene ID
Mm.210155

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.