mouse GLYR1 shRNA silencing Adenovirus

Name 
Ad-m-GLYR1-shRNA
Cat No 
shADV-250956
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Glyr1.

shADV-250956
Ad-m-GLYR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Glyr1 (glyoxylate reductase 1 homolog (Arabidopsis)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2810419J22Rik; 3930401K13Rik; AW545332; Npac
Description (Vector)
GLYR1 may have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).
Gene ID
74022
Gene Name (Vector)
glyoxylate reductase 1 homolog (Arabidopsis)
Gene Symbol
Glyr1
ORF Size (aa)
1641
ORF Size (bp)
1641 bp
RefSeq ID
NM_028720
RefSeq Synonyms
NM_028720, NM_001079814, BC006893,
Species
mouse
UniGene ID
Mm.21652

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.