mouse RUNX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Runx1.
shADV-250906
Ad-m-RUNX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Runx1 (runt related transcription factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AML1; CBF-alpha-2; Cbfa2; Pebp2a2; Pebpa2b
Description (Vector)
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation.
Gene ID
12394
Gene Name (Vector)
runt related transcription factor 1
Gene Symbol
Runx1
ORF Size (aa)
1320
ORF Size (bp)
1320 bp
RefSeq ID
NM_009821
RefSeq Synonyms
NM_009821, NM_001111023, NM_001111022, NM_001111021, BC069929,
Species
mouse
UniGene ID
Mm.4081
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.