human EEF1E1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EEF1E1.
shADV-232011
Ad-h-EEF1E1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AIMP3; P18
Description (Vector)
EEF1E1 encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Gene ID
9521
Gene Name (Vector)
eukaryotic translation elongation factor 1 epsilon 1
Gene Symbol
EEF1E1
HGNC ID
HGNC:3212
ORF Size (aa)
525
RefSeq ID
NM_004280
RefSeq Synonyms
NM_004280, NM_001135650, BC005291,
Species
human
UniGene ID
Hs.719206
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.