human MICB shRNA silencing Adenovirus

Name 
Ad-h-MICB-shRNA
Cat No 
shADV-231124
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MICB.

shADV-231124
Ad-h-MICB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MICB (MHC class I polypeptide-related sequence B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PERB11.2
Description (Vector)
MICB encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides.
Gene ID
4277
Gene Name (Vector)
MHC class I polypeptide-related sequence B
Gene Symbol
MICB
HGNC ID
HGNC:7091
ORF Size (aa)
1023
ORF Size (bp)
1023 bp
RefSeq ID
NM_005931
RefSeq Synonyms
NM_005931, NM_001289161, NM_001289160, BC044218,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.