human GTF3C6 shRNA silencing Adenovirus

Name
Ad-h-GTF3C6-shRNA

Cat No
shADV-230636

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human GTF3C6.

shADV-230636

Ad-h-GTF3C6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GTF3C6 (general transcription factor IIIC subunit 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

bA397G5.3; C6orf51; TFIIIC35

Description (Vector)

RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.(supplied by OMIM, Mar 2008)

Gene ID

112495

Gene Name (Vector)

general transcription factor IIIC subunit 6

Gene Symbol

GTF3C6

HGNC ID

HGNC:20872

ORF Size (aa)

642

RefSeq ID

NM_138408

RefSeq Synonyms

NM_138408, BC011593,

Species

human

UniGene ID

Hs.418520

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.