human S1PR1 shRNA silencing Adenovirus

Name 
Ad-h-S1PR1-shRNA
Cat No 
shADV-230289
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human S1PR1.

shADV-230289
Ad-h-S1PR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human S1PR1 (sphingosine-1-phosphate receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
64
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1
Description (Vector)
S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.
Gene ID
1901
Gene Name (Vector)
sphingosine-1-phosphate receptor 1
Gene Symbol
S1PR1
HGNC ID
HGNC:3165
ORF Size (aa)
1149
ORF Size (bp)
1149 bp
RefSeq ID
NM_001400
RefSeq Synonyms
NM_001400, NM_001320730, BC018650,
Species
human
UniGene ID
Hs.154210

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.