human SPANXA1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SPANXA1.
shADV-230259
Ad-h-SPANXA1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SPANXA1 (sperm protein associated with the nucleus, X-linked, family member A1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CT11.1; NAP-X; SPAN-X; SPAN-Xa; SPAN-Xb; SPANX; SPANX-A
Description (Vector)
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis.
Gene ID
30014
Gene Name (Vector)
sperm protein associated with the nucleus, X-linked, family member A1
Gene Symbol
SPANXA1
HGNC ID
HGNC:11218
ORF Size (aa)
291
RefSeq ID
NM_013453
RefSeq Synonyms
NM_013453, BC148759, BC141462, BC069816, BC069393,
Species
human
UniGene ID
Hs.334464
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.