human ATP1B1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ATP1B1.
shADV-229892
Ad-h-ATP1B1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ATP1B1 (ATPase Na+/K+ transporting subunit beta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATP1B
Description (Vector)
ATP1B1 belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
Gene ID
481
Gene Name (Vector)
ATPase Na+/K+ transporting subunit beta 1
Gene Symbol
ATP1B1
HGNC ID
HGNC:804
ORF Size (aa)
912
ORF Size (bp)
912 bp
RefSeq ID
NM_001677
RefSeq Synonyms
NM_001677, BC000006,
Species
human
UniGene ID
Hs.291196
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.