human SPHK2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SPHK2.
shADV-229096
Ad-h-SPHK2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SPHK2 (sphingosine kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SK 2; SK-2; SPK 2; SPK-2
Description (Vector)
SPHK2 encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
56848
Gene Name (Vector)
sphingosine kinase 2
Gene Symbol
SPHK2
HGNC ID
HGNC:18859
ORF Size (aa)
1857
ORF Size (bp)
1857 bp
RefSeq ID
NM_020126
RefSeq Synonyms
NM_020126, NM_001243876, NM_001204160, NM_001204159, NM_001204158, BC010671, BC006161,
Species
human
UniGene ID
Hs.
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.