human ZFX shRNA silencing Adenovirus

Name
Ad-h-ZFX-shRNA

Cat No
shADV-228230

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ZFX.

shADV-228230

Ad-h-ZFX-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ZFX (zinc finger protein, X-linked). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ZNF926

Description (Vector)

ZFX on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Gene ID

7543

Gene Name (Vector)

zinc finger protein, X-linked

Gene Symbol

ZFX

HGNC ID

HGNC:12869

ORF Size (aa)

2535

ORF Size (bp)

2535 bp

RefSeq ID

NM_003410

RefSeq Synonyms

NM_003410, NM_001330327, NM_001178095, NM_001178086, NM_001178085, NM_001178084, BC136309, BC136308,

Species

human

UniGene ID

Hs.336681

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.