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human ZFX shRNA silencing AAV

Name 
AAV-h-ZFX-shRNA
Cat No 
shAAV-228230
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ZFX.

shAAV-228230
AAV-h-ZFX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ZFX (zinc finger protein, X-linked). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ZNF926
Description (Vector)
ZFX on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.
Gene ID
7543
Gene Name (Vector)
zinc finger protein, X-linked
Gene Symbol
ZFX
HGNC ID
HGNC:12869
ORF Size (aa)
2535
ORF Size (bp)
2535 bp
RefSeq ID
NM_003410
RefSeq Synonyms
NM_003410, NM_001330327, NM_001178095, NM_001178086, NM_001178085, NM_001178084, BC136309, BC136308,
Species
human
UniGene ID
Hs.336681

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.