human XPNPEP3 shRNA silencing Adenovirus

Name 
Ad-h-XPNPEP3-shRNA
Cat No 
shADV-227912
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human XPNPEP3.

shADV-227912
Ad-h-XPNPEP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human XPNPEP3 (X-prolyl aminopeptidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
APP3; ICP55; NPHPL1
Description (Vector)
XPNPEP3 belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.
Gene ID
63929
Gene Name (Vector)
X-prolyl aminopeptidase 3
Gene Symbol
XPNPEP3
HGNC ID
HGNC:28052
ORF Size (aa)
837
RefSeq ID
NM_022098
RefSeq Synonyms
NM_022098, NM_001204827, BC004989, BC001681, BC001208,
Species
human
UniGene ID
Hs.529163

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.