human XDH shRNA silencing Adenovirus

Name 
Ad-h-XDH-shRNA
Cat No 
shADV-227879
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human XDH.

shADV-227879
Ad-h-XDH-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human XDH (xanthine dehydrogenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
XAN1; XO; XOR
Description (Vector)
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Gene ID
7498
Gene Name (Vector)
xanthine dehydrogenase
Gene Symbol
XDH
HGNC ID
HGNC:12805
ORF Size (aa)
4002
ORF Size (bp)
4002 bp
RefSeq ID
NM_000379
RefSeq Synonyms
NM_000379, BC166696,
Species
human
UniGene ID
Hs.250

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.