human XAF1 shRNA silencing Adenovirus

Name 
Ad-h-XAF1-shRNA
Cat No 
shADV-227863
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human XAF1.

shADV-227863
Ad-h-XAF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human XAF1 (XIAP associated factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BIRC4BP; HSXIAPAF1; XIAPAF1
Description (Vector)
XAF1 encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
54739
Gene Name (Vector)
XIAP associated factor 1
Gene Symbol
XAF1
HGNC ID
HGNC:30932
ORF Size (aa)
906
RefSeq ID
NM_017523
RefSeq Synonyms
NM_199139, NM_017523, BC073156,
Species
human
UniGene ID
Hs.441975

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.