human WASF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human WASF1.
shADV-227597
Ad-h-WASF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human WASF1 (WAS protein family member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SCAR1; WAVE; WAVE1
Description (Vector)
WASF1, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
8936
Gene Name (Vector)
WAS protein family member 1
Gene Symbol
WASF1
HGNC ID
HGNC:12732
ORF Size (aa)
1680
ORF Size (bp)
1680 bp
RefSeq ID
NM_003931
RefSeq Synonyms
NM_003931, NM_001024936, NM_001024935, NM_001024934, BC044591,
Species
human
UniGene ID
Hs.75850
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.