human VPS37A shRNA silencing Adenovirus

Name 
Ad-h-VPS37A-shRNA
Cat No 
shADV-227534
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human VPS37A.

shADV-227534
Ad-h-VPS37A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VPS37A (VPS37A, ESCRT-I subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ESCRT-I complex subunit VPS37A; HCRP1; hepatocellular carcinoma-related protein 1; hVps37A; polyglutamine binding protein 2; PQBP2; SPG53; vacuolar protein sorting 37 homolog A; vacuolar protein sorting-associated protein 37A
Description (eCommerce)
Vacuolar protein sorting-associated protein 37A (VPS37A) is a component of the ESCRT-I complex, a regulator of vesicular trafficking process. It is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. VPS37A may be involved in cell growth and differentiation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NEZ2].
Gene ID
137492
Gene Name (eCommerce)
VPS37A, ESCRT-I subunit
Gene Name (Vector)
VPS37A, ESCRT-I subunit
Gene Symbol
VPS37A
HGNC ID
HGNC:24928
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
Protein Name (eCommerce)
Vacuolar protein sorting-associated protein 37A
RefSeq ID
NM_152415
RefSeq Synonyms
NM_152415, NM_001145152, BC067754, BC022363,
Research Areas
Apoptosis,Host-Virus Interactions,Neurobiology,Neurodegeneration
Research Areas (Faceted)
cell_biology,infectious_disease,neurobiology
Species
human
Target Sentence
Vacuolar protein sorting-associated protein 37A (VPS37A) is a component of the ESCRT-I complex, a regulator of vesicular trafficking process. It is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. VPS37A may be involved in cell growth and differentiation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NEZ2].
UniGene ID
Hs.343873
UniProt ID (eCommerce)
Q8NEZ2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.