human VDAC1 shRNA silencing Adenovirus

Name 
Ad-h-VDAC1-shRNA
Cat No 
shADV-227449
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human VDAC1.

shADV-227449
Ad-h-VDAC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VDAC1 (voltage dependent anion channel 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PORIN; VDAC-1
Description (Vector)
VDAC1 encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
Gene ID
7416
Gene Name (Vector)
voltage dependent anion channel 1
Gene Symbol
VDAC1
HGNC ID
HGNC:12669
ORF Size (aa)
852
RefSeq ID
NM_003374
RefSeq Synonyms
NM_003374, BC090042, BC071168, BC008482,
Species
human
UniGene ID
Hs.519320

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.