mouse POU domain, class 5, transcription factor 1 (POU5F1) Adenovirus
Using adenovirus to deliver these transcription factors has 2 main advantages - it does not incorporate into the targeted host and therefore avoids the potential for insertional mutagenesis, and the expression is transient for a brief amount of time in order for effective reprogramming to take place.
This adenovirus expresses mouse Oct3/4, and it can be used in combination with other iPSC factor for the induction of iPSC reprogramming.
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- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- CMV (ubiquitous)
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- 1x10^10 PFU/ml
- Gene Symbol
- POU domain, class 5, transcription factor 1
- Gene ID
- Gene Synonyms
- Oct-3; Oct-3/4; Oct-4; Oct3; Oct3/4; Oct4; Otf-3; Otf-4; Otf3; Otf3-rs7; Otf3g; Otf4