human VAMP7 shRNA silencing Adenovirus

Name
Ad-h-VAMP7-shRNA

Cat No
shADV-227389

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human VAMP7.

shADV-227389

Ad-h-VAMP7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VAMP7 (vesicle associated membrane protein 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

SYBL1; synaptobrevin-like 1; synaptobrevin-like protein 1; tetanus neurotoxin-insensitive VAMP; tetanus-insensitive VAMP; TIVAMP; TI-VAMP; VAMP-7; vesicle-associated membrane protein 7

Description (eCommerce)

Vesicle-associated membrane protein 7 (VAMP7) is a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. VAMP7 localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes [taken from NCBI Entrez Gene (Gene ID: 6845)].

Description (Vector)

VAMP7 encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.

Gene ID

6845

Gene Name (eCommerce)

vesicle associated membrane protein 7

Gene Name (Vector)

vesicle associated membrane protein 7

Gene Symbol

VAMP7

HGNC ID

HGNC:11486

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

663

Protein Name (eCommerce)

Vesicle-associated membrane protein 7

RefSeq ID

NM_005638

RefSeq Synonyms

NM_005638, NM_001185183, NM_001145149, BC056141,

Research Areas

Golgi Apparatus,Immunology,Lysosomal Transport,Lysosome,Neurobiology,Synapse,Transport

Research Areas (Faceted)

cell_biology,immunology,neurobiology

Species

human

Target Sentence

Vesicle-associated membrane protein 7 (VAMP7) is a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. VAMP7 localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes [taken from NCBI Entrez Gene (Gene ID: 6845)].

UniGene ID

Hs.24167

UniProt ID (eCommerce)

P51809

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.