human USP4 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

USP4

Gene Name

ubiquitin specific peptidase 4

Gene ID

7375

Gene Synonyms

UNP; Unph

ORF Size

2892 bp

RefSeq#

NM_003363

Gene Description

USP4 is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.714416

HGNC ID

HGNC:12627