human UHRF2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human UHRF2.
shADV-227166
Ad-h-UHRF2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human UHRF2 (ubiquitin like with PHD and ring finger domains 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NIRF; RNF107; TDRD23; URF2
Description (Vector)
UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
Gene ID
115426
Gene Name (Vector)
ubiquitin like with PHD and ring finger domains 2
Gene Symbol
UHRF2
HGNC ID
HGNC:12557
ORF Size (aa)
1512
ORF Size (bp)
1512 bp
RefSeq ID
NM_152896
RefSeq Synonyms
NM_152896, BC028397,
Species
human
UniGene ID
Hs.493401
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.