human UGCG shRNA silencing Adenovirus

Name
Ad-h-UGCG-shRNA

Cat No
shADV-227133

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human UGCG.

shADV-227133

Ad-h-UGCG-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human UGCG (UDP-glucose ceramide glucosyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GCS; GLCT1

Description (Vector)

Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation.

Gene ID

7357

Gene Name (Vector)

UDP-glucose ceramide glucosyltransferase

Gene Symbol

UGCG

HGNC ID

HGNC:12524

ORF Size (aa)

1185

ORF Size (bp)

1185 bp

RefSeq ID

NM_003358

RefSeq Synonyms

NM_003358, BC038711,

Species

human

UniGene ID

Hs.593014

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.