human TWF1 shRNA silencing Adenovirus

Name 
Ad-h-TWF1-shRNA
Cat No 
shADV-226876
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TWF1.

shADV-226876
Ad-h-TWF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TWF1 (twinfilin actin binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
A6; A6 protein tyrosine kinase; protein A6; protein tyrosine kinase 9; PTK9; PTK9 protein tyrosine kinase 9; twinfilin, actin-binding protein, homolog 1; twinfilin-1
Description (eCommerce)
Twinfilin-1 is an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1 [taken from NCBI Entrez Gene (Gene ID: 5756)].
Description (Vector)
TWF1 encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.
Gene ID
5756
Gene Name (eCommerce)
twinfilin actin binding protein 1
Gene Name (Vector)
twinfilin actin binding protein 1
Gene Symbol
TWF1
HGNC ID
HGNC:9620
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
759
Protein Name (eCommerce)
Twinfilin-1
RefSeq ID
NM_002822
RefSeq Synonyms
NM_002822, NM_001242397, BC043148, BC022344,
Research Areas
Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Twinfilin-1 is an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1 [taken from NCBI Entrez Gene (Gene ID: 5756)].
UniGene ID
Hs.189075
UniProt ID (eCommerce)
Q12792

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.