human TPI1 shRNA silencing Adenovirus

Name 
Ad-h-TPI1-shRNA
Cat No 
shADV-226264
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TPI1.

shADV-226264
Ad-h-TPI1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TPI1 (triosephosphate isomerase 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
epididymis secretory protein Li 49; HEL-S-49; TIM; TPI; TPID; triosephosphate isomerase; triose-phosphate isomerase
Description (eCommerce)
TPP1 is involved in telomere function and is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, TPP1 plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere [taken from NCBI Entrez Gene (Gene ID: 65057].
Description (Vector)
TPI1 encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
Gene ID
7167
Gene Name (eCommerce)
triosephosphate isomerase 1
Gene Name (Vector)
triosephosphate isomerase 1
Gene Symbol
TPI1
HGNC ID
HGNC:12009
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
759
Protein Name (eCommerce)
Triosephosphate isomerase
RefSeq ID
NM_000365
RefSeq Synonyms
NM_001258026, NM_001159287, NM_000365, BC070129, BC017917, BC015100, BC011611, BC009329, BC007812, BC007086,
Research Areas
Metabolism/Metabolic Process,Neurobiology
Research Areas (Faceted)
cell_biology,metabolism,neurobiology
Species
human
Target Sentence
TPP1 is involved in telomere function and is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, TPP1 plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere [taken from NCBI Entrez Gene (Gene ID: 65057].
UniGene ID
Hs.524219
UniProt ID (eCommerce)
P60174

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.