human TOLLIP shRNA silencing Adenovirus

Name 
Ad-h-TOLLIP-shRNA
Cat No 
shADV-226174
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TOLLIP.

shADV-226174
Ad-h-TOLLIP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TOLLIP (toll interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IL-1RAcPIP
Description (Vector)
TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase.
Gene ID
54472
Gene Name (Vector)
toll interacting protein
Gene Symbol
TOLLIP
HGNC ID
HGNC:16476
ORF Size (aa)
825
RefSeq ID
NM_019009
RefSeq Synonyms
NM_019009, NM_001318516, NM_001318515, NM_001318514, NM_001318512, BC018272, BC012057, BC004420,
Species
human
UniGene ID
Hs.368527

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.