human TMPRSS11D shRNA silencing Adenovirus

Name
Ad-h-TMPRSS11D-shRNA

Cat No
shADV-226006

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TMPRSS11D.

shADV-226006

Ad-h-TMPRSS11D-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TMPRSS11D (transmembrane protease, serine 11D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

HAT

Description (Vector)

TMPRSS11D encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.

Gene ID

9407

Gene Name (Vector)

transmembrane protease, serine 11D

Gene Symbol

TMPRSS11D

HGNC ID

HGNC:24059

ORF Size (aa)

1257

ORF Size (bp)

1257 bp

RefSeq ID

NM_004262

RefSeq Synonyms

NM_004262, BC125196, BC125195,

Species

human

UniGene ID

Hs.132195

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.